Ireland flyhalf Sam Prendergast will start his first Six Nations game in Saturday's opener against England and marshal an almost full strength side as the holders bid to win a third successive title for the first time.

The Six Nations starts on Friday and the annual jamboree between the top rugby nations in the northern hemisphere isn’t short of storylines for the 2025 edition.

Position by Position, Ireland's rugby legends assess the candidates and pick their XV to start the opening Six Nations game against England in Dublin

England will give Harlequins winger Cadan Murley his debut against Ireland on Saturday after Steve Borthwick named his team on Tuesday for the Six Nations opener, with twins Ben and Tom Curry to start in the back row together for the first time.

SAM PRENDERGAST HAS been selected to start at out-half for Ireland in their Six Nations opener against England on Saturday at the Aviva Stadium [KO 4.45pm, Virgin Media One]. The 21-year-old will make his Six Nations debut in the Dublin clash,

Sam Prendergast will be in the spotlight when Ireland begin their quest for an unprecedented third successive Six Nations title against England in Dublin on Saturday. England have not finished higher than third since last winning the Six Nations in 2020 and they arrive in Dublin with an off-field crisis engulfing the Rugby Football Union.